|The CDC suggests follow-up treatment at 6, 24, and 48 hours after the initial dose. For people with kidney disease: You should not take this drug if you have kidney disease or kidney damage. Inadvertent Intravenous Administration 17. The serum concentration of Ibrutinib can be increased when it is combined with Clarithromycin. Flagyl ER 750 mg tablets are indicated in the treatment of BV in non-pregnant women. However, elderly patients are more likely to have age-related heart problems, which may require caution and an adjustment in the dose for patients receiving albuterol.